Dr Karla Neves

Lecturer

Strathclyde Institute of Pharmacy and Biomedical Sciences

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Personal statement

Dr Neves is a Lecturer and Researcher within the Strathclyde Institute of Pharmacy & Biomedical Sciences at the University of Strathclyde in Glasgow, UK. She has been awarded a PhD in Sciences in 2016 at the University of Sao Paulo, Brazil, and worked as a Research Associate until 2022 in the University of Glasgow with Prof. Rhian Touyz.

 

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Publications

Humanising nanotoxicology : replacement of animal-derived products in the application of integrated approaches to testing and assessment of nanomaterial inhalation hazard
Fraser Roma, Campbell Keira, Pokorski Pawel, Mackinnon Eve, McAllister Katie, Neves Karla B, Murphy Fiona
Frontiers in Bioengineering and Biotechnology Vol 13 (2025)
https://doi.org/10.3389/fbioe.2025.1526808
P169 VEGF inhibition-induced PARP overactivation leads to endothelial dysfunction and inflammation : role of Sirtuin 1 signalling
Neves Karla, Alves-Lopes Rheure, Montezano Augusto, Touyz Rhian
(2024)
https://doi.org/10.1097/01.hjh.0001063548.35277.58
Editorial: The interplay between oxidative stress, immune cells and inflammation in cardiovascular diseases
Nosalski R, Siedlinski M, Neves K B, Monaco C
Frontiers in Cardiovascular Medicine Vol 11 (2024)
https://doi.org/10.3389/fcvm.2024.1385809
Vasoprotective effects of NOX4 are mediated via polymerase and transient receptor potential melastatin 2 cation channels in endothelial cells
Alves-Lopes Rheure, Lacchini Silvia, Neves Karla B, Harvey Adam, Montezano Augusto C, Touyz Rhian M
Journal of Hypertension Vol 41, pp. 1389-1400 (2023)
https://doi.org/10.1097/HJH.0000000000003478
SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication
Montezano Augusto C, Camargo Livia L, Mary Sheon, Neves Karla B, Rios Francisco J, Stein Ross, Lopes Rheure A, Beattie Wendy, Thomson Jacqueline, Herder Vanessa, Szemiel Agnieszka M, McFarlane Steven, Palmarini Massimo, Touyz Rhian M
Scientific Reports Vol 13 (2023)
https://doi.org/10.1038/s41598-023-41115-3
Vascular mechanisms of post-COVID-19 conditions : rho-kinase is a novel target for therapy
Sykes Robert A, Neves Karla B, Alves-Lopes Rhéure, Caputo Ilaria, Fallon Kirsty, Jamieson Nigel B, Kamdar Anna, Legrini Assya, Leslie Holly, McIntosh Alasdair, McConnachie Alex, Morrow Andrew, McFarlane Richard W, Mangion Kenneth, McAbney John, Montezano Augusto C, Touyz Rhian M, Wood Colin, Berry Colin
European Heart Journal Vol 9, pp. 371-386 (2023)
https://doi.org/10.1093/ehjcvp/pvad025

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Research Interests

Her research interests are in understanding molecular and vascular mechanisms associated with cardiovascular and metabolic diseases, with a particular interest in the cardiovascular effects of anti-cancer drugs. She has a large expertise in vascular function, vascular smooth muscle cells and endothelial pathways, nitric oxide and oxidative stress, using a multidisciplinary approach with both in vitro and in vivo models of vascular function in health and disease.

 

Professional Activities

SEX-DEPENDENT MITOCHONDRIAL FUNCTION IN THE RIGHT VENTRICLE IN PULMONARY ARTERIAL HYPERTENSION
Examiner
9/10/2024
Assessing Jagged1 redox signalling mechanisms following quantitative analysis of the endothelial redox proteome
Examiner
22/8/2024
Assessing the role of JNK in Human Endothelial Cell Death Induced by Anti-Cancer Therapies
Examiner
19/7/2024
The Role of 16α-Hydroxyestradiol in Pulmonary Arterial Hypertension
Examiner
24/6/2024
SIPBS Open Doors Day
Chair
8/6/2024
Science PGT Workshop
Participant
27/6/2023

More professional activities

Projects

TRPM7 and Notch vascular signalling: new targets to improve coronary collateral circulation after acute myocardial infarction?
Neves, Karla (Principal Investigator)
01-Jan-2024 - 28-Jan-2026
Cardiovascular effects of the anti-cancer combination therapy with VEGF inhibitors and immune checkpoint inhibitors
Neves, Karla (Principal Investigator)
01-Jan-2023 - 28-Jan-2024
Cardiovascular effects of a novel combination therapy in cancer treatment
Neves, Karla (Principal Investigator)
31-Jan-2023 - 30-Jan-2025

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Contact

Dr Karla Neves
Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences

Email: karla.neves@strath.ac.uk
Tel: 548 3430